12/18/2023 0 Comments Interactive notebooks![]() He even has an SE teacher to help keep it organized and it’s still not enough and this takes time away from doing other things like working on classwork that he is behind on. I miss the textbook at least it was legible and organized, everything my son’s INB is not. You can tell me how great it is, but for us it just isnt. I dont see why INB and textbooks cant work in unison. I want to throw it across the room, set it on fire and throw it in the trash. It hurts my brain just to look at it, I know his view is not much different. I also have adhd, and he brings these apparently “miracle inb” and I just feel so helpless because it is not helpful. I know because this is the second year we have been dealing w/this INB.Īt least w/a binder he could just put them in the binder w/o worrying about glueing something in, and if those get lost at least he would have a textbook to fall back on. This idea assumes that anyone can do it, and it’s just not the case for us. It’s just one more thing for him to worry about. It’s his chaotic unorganized distracted frustrated brain all in a 3d miracle INB. ![]() It just emphasizes and expresses how his brain works. What I wouldnt do to have a textbook at least as a backup.Īn INB does not help my son who has severe adhd w/a math disability to stay organized at all. ![]() I often have to try and organize it for him which is difficult when I dont know what goes where. everything is out of order, he loses worksheets because they get torn (because even when they get glued in they stick out or only partially glued in) or not glued in properly. My son struggles w/this “INB” it’s a disaster. When i read your formatting it appears the opposite of what i have researched – this copy and pasting from NSTA did nt align correctly but you can see input on the right is from teacher ( lectures, notes etc) left side is output from student synthesisĪs a parent of a special education student, I personally loathe the INB. Resource note: For online graphic organizers try This is where you put incoming information: notes, data, and so on. All rights reserved.This is where you personally connect with the information on the attached right side page ĭata Commons Jupyter Notebook RNA-seq bioinformatics data visualization enrichment analysis pipeline systems biology.Ĭopyright © 2018 Elsevier Inc. BioJupies is freely available as a web-based application from. By providing an intuitive user interface for notebook generation for RNA-seq data analysis, starting from the raw reads all the way to a complete interactive and reproducible report, BioJupies is a useful resource for experimental and computational biologists. The notebooks are downloadable, customizable, and can run within a Docker container. ![]() The notebooks are permanently stored in the cloud and made available online through a persistent URL. Generated notebooks have the executable code of the entire pipeline, rich narrative text, interactive data visualizations, differential expression, and enrichment analyses. Through an intuitive interface, novice users can rapidly generate tailored reports to analyze and visualize their own raw sequencing files, gene expression tables, or fetch data from >9,000 published studies containing >300,000 preprocessed RNA-seq samples. BioJupies is a web application that enables the automated creation, storage, and deployment of Jupyter Notebooks containing RNA-seq data analyses.
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12/18/2023 0 Comments Presentify windows![]()
12/18/2023 0 Comments Book of demons platforms![]() In the original version, once you interacted with the archstone you were only able to return to The Nexus. Once you defeat a Boss in Demon's Souls Remake, if you touch the Archstone you now can move within that World's Archstones besides being able to return to The Nexus. See Maps for detailed maps of all Demon's Souls Locations.You can visit our Game Progress Route and Walkthrough pages for a comprehensive guide on how to beat the game following the difficulty level.Example: If a player refers to 1-2 he is Taking about Phalanx Archstone, World 1, Division 2. The first number represents the World, while the second number represents the division or location inside that particular World. Players often refer to Locations by number, for example 1-3 or 4-3. There are 5 Worlds, each of them divided into different Locations. Locations in Demon's Souls are divided into different Worlds. All Archstones can be accessed from The Nexus. This page covers a list of the various areas that can be discovered in the game.Īfter defeating the first Boss, Phalanx, players will be free to decide the order of the Archstones (Worlds) that they visit. Players can encounter and discover various Enemies, Bosses, NPCs, types of equipment, and much more for each Location. ![]() If you want to be notified when the games are released, wishlist the games on Steam or simply subscribe to our newsletter.Locations in Demon's Souls and Demon's Souls Remake covers the different areas that can be explored in the game. If you are excited about Hellcard and Book of Aliens, and want to follow their development, be sure to join our Sneek-Peek discord channel. The good news is that new games are coming along nicely and we can finally focus on them, as the biggest hurdles are behind us. We moved a little over a month ago and it’s still not complete, but at least everyone’s got a place to sit and work. Save the terror-stricken Paperverse from the clutches of the Archdemon himself Book of Demons takes place in Paperverse, a world that. Wield magic cards instead of weapons and slay the armies of darkness in the dungeons below the Old Cathedral. Sadly, it was a mess and needed full remodeling. Book of Demons is a Hack & Slash Deck-building hybrid in which YOU decide the length of quests. ![]() We found a very nice place in a good location and capable of accommodating our bigger team. Our team is now 10 people and we are still looking for a community manager.īy far, the biggest amount of time in 2019 sunk into moving to our new office. But thanks to the new people on board (two graphic artists and a designer) we were able to kick off a simultaneous development of Hellcard and Book of Aliens. We also dedicated a significant amount of time to expanding the team. Learning a new technology can be a big endeavor on its own, but it’s an investment that should allow us to make better games faster in the future. This was when we came to the conclusion that Hellcard would be the last title made in our current technology and that we need to make the switch to a mainstream modern engine with Book of Aliens. Expect an announcement about it soon.Ī considerable amount of time was dedicated to a thorough review of our technology stack and planning of future features. Luckily, in the middle of the year, we were approached by a publisher who offered to port the game and bring it to even more platforms. As you know from our previous announcements, we were working on an Xbox One version of the game. It takes place in the same universe as Book of Demons, but takes the story further and into unexpected places!īook of Demons used cards for many of its mechanics and we have toyed with the idea of making a truly deckbuilding mode on top of it, but within the original game it could never be developed to its full potential.Īpart from this, we were (and still are) working on an iPad port of Book of Demons and this is coming along nicely and is almost complete. Hellcard is a cooperative roguelike deckbuilder supporting both single and multiplayer modes. But most important of all, today we’re announcing not one, but two new games that we are working on in the Return 2 Games series! Book of Demons: HELLCARD ![]() In the spirit of the annual roadmap update, I’ll try to briefly sum up what we managed to do, what’s coming up in the near and not so near future, and – as usual – why everything is always going slower than we’d like to. 2019 was a particularly chaotic time for all of us here at Thing Trunk! A whole year has passed since Book of Demons went out of Early Access, so it’s high time we share with you what we’ve been up to for the last 12 months. 12/18/2023 0 Comments Ryobi multi tool blades![]()
12/18/2023 0 Comments Pokemon wiki hapu![]() The Main Reason Eleanor Miller Played Misty Because they're Both Tomboys.Chip was Forrest, and Dale was Brock in DinosaurKingRockz's TV spoof, Pokemon (DinosaurKingRockz Animal Style).and Misty was Eleanor Miller In Ooglyeye's Spoof ? Ketchum and the Boys (1983).Pokemon Sword and Shield (Chris1703 Style).Pokemon Diamond and Pearl (Chris1703 Style).Pokemon Advanced Generation (Chris1703 Style).Pokemon Mewtwo Returns (Chris1703 Style).Pokemon The Movie 2000 (Chris1703 Style).Pokemon The First Movie (Chris1703 Style).Damian - Rat Capone (Chip 'n Dale Rescue Rangers).Joe - Squeaky the Supercat (Krypto the Superdog).Giselle - Princess (Krypto the Superdog).Lily - Jeanette Miller (Alvin and the Chipmunks).Violet - Tammy (Chip 'n Dale Rescue Rangers).Forrest - Skippy The Squirrel (Animaniacs).Flint - Alvin Seville (Alvin and the Chipmunks).Professor Oak - Thomas O'Malley (The Aristocats).James - Mojo Jojo (The Powerpuff Girls).Delia ketchum - Sylvia (An Extremely Goofy Movie).Brock - Chip (Chip 'n Dale Rescue Rangers).Misty - Eleanor Miller (Alvin and the Chipmunks).This is the only region which is not confirmed to appear in any Journeys episodes so far.The adjectival form of Alola is "Alolan".However, the Alola League is the only Pokemon League that Ash won that is in the games as well as the anime. The Alola Pokémon League is currently the only actual Pokémon League Ash ever actually won, besides the Orange League.The Kantonian Gym is located in Malie City on Ula'ula Island, although it is only present in Ultra Sun and Ultra Moon and it does not give any badges. Technically, there is one gym in the region. Having to tend to the fields every morning has made me an early riser.' During special log-in conversation (morning) 'It is good to wake up early You should make the most of the time you have' During special log-in conversation (afternoon) 'Good afternoon, friend Now is the time to relax and take a stroll.It is the first game in the main series without the gym system.So far we have a crazy 80,583 total edits on this wiki Pokémon art is provided by Popkas. In its anime adaption's episode SM100 and SM101, an alternate dimension of Alola exist, and it is based on the game's Ultra Ruin, until Guzzlord's defeat. This wiki contains everything you should need to know about the fangame Pokémon Uranium, from Pokémon movesets and character biographies to tips and strategies on how to progress in the game.Victory Road is also absent instead, the player character travels up Mount Lanakila.However, thanks to the efforts of Professor Kukui, two Kahunas, one Trial Captain, and one past victor of the Isle Challenge become the Alola Elite Four, while the player character becomes the Champion. Until the events of the game, there wasn't even an Elite Four or a Champion.This is the only main series game region which does not have Gym Leaders. ![]() This is the second region to not introduce new Fossil Pokémon, the first being Johto.Similar to people in Hawaii, Alolan people use "Alola" as a word of greetings.This is the only region to have Legendary Pokémon to have Evolved forms.The two legendary Pokémon are Solgaleo, resembling a lion with a sun motif, and Lunala, resembling a bat with a moon motif.It is also worth noting that this is the first region with a palindromic name.This is also the third region to based on a location in the US (Hawaii), the first is Orre (based on Arizona) and the second is Unova (which is based on the New York City metropolitan area).Alola's name comes from the Hawaiian greeting, "Aloha".Island Challenge Trial Captains NameĪn artwork of some Pokémon found in Alola. The Alola region consists of four main islands and one artificial island. 12/18/2023 0 Comments Record it now appIt allows you to simultaneously record with microphone and system sounds, add annotation to the recording, clip the recordings, export as multiple formats, etc. It has all the features that you may need in capturing a high-quality video clip of your actions on computer screen, which can be used in many cases, like gameplay, online meeting, and live stream recoding. Limited free plan that only allows 90 seconds/recording.įonePaw Screen Recorder is a powerful screencasting software for Windows and Mac computer.There’s also lots of handy extra features you can use (video annotations, advanced analytics, do-not-disturb mode, etc.) so you don’t need other third-party tools. It’s a quick solution if you need to create GIFs often.Pricing: Paid plans start at $9.95/user/month. When you finish your screen recording, a link is made available for you to instantly share in Slack, Google Suite, Asana, Trello, or anywhere else you collaborate with your co-workers. Its screen recording feature offers quick controls to enable full-screen recording, audio-only, or webcam-enabled recordings. So while you won’t have to worry about missing features, it’s not a fit if you don’t regularly use it.ĬloudApp provides end-to-end visual communication with its screen recording, GIF creating, and screenshot capturing product. It’s one of the most expensive choices on this list but the price is motivated by its complexity.There’s also a built-in assets library you can use for intros, backgrounds, icons, etc. Camtasia comes with advanced screen recording and presenting features, even allowing you to add interactive quizzes to your videos.For new users who are afraid of slow learning curves, Camtasia provides clear and easy-to-understand tutorial videos that take you through everything you need to get started. It has a built-in editor so you won’t need to export your videos to another software for editing. With Camtasia, you can record virtually anything on your computer screen whether it be websites, software, video calls, or presentations. CamtasiaĬamtasia is your first go-to screen recording editor tool. You can also use Krisp to cancel chattering during live events and meetings on Zoom, Google Meet, and more.īest screen recording apps for Mac 1. Along with its HD voice feature, it will ensure your recordings sound just like studio ones,- without requiring post-production sound quality editing. You can use Krisp noise cancelling app to remove background noise and echoes on your recordings. Don’t worry too much about sound editing options.Note that some tools won’t allow you to test all features for free so reach out to their customer support team to see if they can offer a demo. Give the trial version a test before making the purchase. ![]() ![]() Once you’re on a tight budget, also pay attention to how many users you can add to one plan. Opt for multi-platform tools if you have a large team or just need the tool to be available anywhere.Divide these into must-have and nice-to-have features. When making your initial list of best screen recording software, go through these steps: But first, let’s have a look at the general points to keep in mind. We’ve tested 12 of the best screen recording apps for Mac, Chrome, and Windows to help you decide which one is best suited for your needs. On top of this, you’ll want to consider the complexity of the app, available assets libraries, collaboration options, and integrations with tools you’re already using. Some tools also allow you to edit the recording, turn it into a full-fledged presentation or course, and even stream it. With most screen recording apps you can record everything you do on screen (or on a section of your screen). ![]() From creating YouTube videos, tutorials, product demos for your prospects, courses for your students or employees, and you can even rely on some to support your articles with GIFs. The best thing about screen recording tools is that there are so many ways to use them. 12/18/2023 0 Comments Gw2 chaperone![]() Some core PcG proteins, such as Enhancer of Zeste (E(z)), Suppressor of Zeste (12) (Su(z)12), and Extra Sex Combs (ESC), are conserved in plants. Polycomb group proteins (PcG) play important roles in epigenetic regulation of gene expression. We suggest that the nuclear-localized OsiEZ1 has a role in regulating various aspects of plant development, and this control is most likely brought about by repressing the activity of downstream regulatory genes. The expression of OsiEZ1 complemented a set1Delta Saccharomyces cerevisiae mutant that is impaired in telomeric silencing. The OsiEZ1/GUS recombinant protein was confined to the nucleus in living cells of particle-bombarded onion peels. The OsiEZ1 transcript was barely detectable in mature zygotic embryos, but its levels were significantly higher in callus derived from rice scutellum, somatic embryos and young seedlings. ![]() Expression studies revealed that the OsiEZ1 transcript level was highest in rice flowers, almost undetectable in developing seeds of 1-2 days post-fertilization but increased significantly in young seeds of 3-5 days post-fertilization. Southern analysis indicates that OsiEZ1 is represented as single copy in the rice genome. In the rice genome, a 7499 bp long OsiEZ1 sequence is split into 17 exons interrupted by 16 introns. All the characteristic domains known to be conserved in E(Z) homologs (subgroup I) of SET domain containing proteins are present in OsiEZ1. The OsiEZ1 cDNA is 3133 bp long with an ORF of 2799 bp, and the predicted amino acid sequence (895 residues) corresponds to a protein of ca. subspecies indica) cDNA, OsiEZ1, as a monocot member of this family. We report here the isolation and characterization of rice (Oryza sativa L. Homologs of all four classes have been characterized in yeast, mammals and plants. The SET domain proteins are divided into four subgroups as categorized by their Drosophila members enhancer of zeste (E(Z)), trithorax (TRX), absent small or homeotic 1 (ASH1) and supressor of variegation (SU(VAR)3-9). The SET domains are conserved amino acid sequences present in chromosomal proteins that contribute to the epigenetic control of gene expression by altering regional organization of the chromatin structure. 12/17/2023 0 Comments Ffxiv wallpaper wizard![]() Grants 3 Umbral Hearts upon casting Freeze. Increases damage dealt by 5% while under the effect of Astral Fire or Umbral Ice. Grants a 40% chance that after casting Fire, your next Fire III will require no MP and have no casting time. Increases base action damage and HP restoration by 30%. Grants a 10% chance that after each damage over time tick inflicted by Thunder or Thunder III (3% for Thunder II or Thunder IV), the next Thunder, Thunder II, Thunder III, or Thunder IV will add its full damage over time amount to its initial damage, have no cast time, and cost no MP.Īllows the stacking of a third Astral Fire and Umbral Ice. Increases base action damage and HP restoration by 10%.Īllows the stacking of a second Astral Fire and Umbral Ice. Puts target and all nearby enemies to sleep.Ĭasting of certain fire and ice spells will grant a stack of Astral Fire and Umbral Ice respectively. ![]() Lowers target's physical damage dealt by 5% and magic damage dealt by 10%. Grants 6 stacks of Soul Resonance, upgrading Fire to Flare and Blizzard to Freeze. Effect ends upon reuse or execution of another action. Reduces damage taken by 90% and grants immunity to Stun, Heavy, Bind, Silence, Half-asleep, Sleep, Deep Freeze, and knockback and draw-in effects. Removes Stun, Heavy, Bind, Silence, Half-asleep, Sleep, and Deep Freeze. Casting will be interrupted when damage is taken. Rush to a targeted enemy's or party member's location.ĭeals damage to nearby enemies with a potency of 3,000 up to a maximum of 9,000 for every stack of Astral Warmth or Umbral Freeze they have accumulated.ĭeals fire damage with a potency of 6000.ĭeals fire damage with a potency of 12,000 to target and all enemies nearby it.ĭeals ice damage with a potency of 12,000 to target and all enemies nearby it.ĭeals unaspected damage with a potency of 16000 to target and all enemies nearby it. The next three spells will require no cast time.ĭeals unaspected damage to target and all enemies nearby it with a potency of 560 for the first enemy, and 60% less for all remaining enemies.ĭeals unaspected damage with a potency of 760.ĭeals fire damage with a potency of 140 to target and all enemies nearby it.ĭeals ice damage with a potency of 140 to target and all enemies nearby it.ĭeals unaspected damage with a potency of 500.ĭeals fire damage with a potency of 4,000.ĭeals ice damage with a potency of 4,000.ĭeals lightning damage to all nearby enemies with a potency of 16,000.ĭeals unaspected damage with a potency of 8,000.Īfflicts target and all enemies nearby it with Half-asleep. Move instantly to Ley Lines drawn by you. Swaps Astral Fire with a single Umbral Ice or Umbral Ice with a single Astral Fire.ĭeals lightning damage with a potency of 30.ĭeals ice damage with a potency of 100 to target and all enemies nearby it.ĭeals unaspected damage with a potency of 100.ĭeals fire damage with a potency of 100 to target and all enemies nearby it.ĭeals lightning damage with a potency of 50 to target and all enemies nearby it.Ĭreates a barrier that nullifies damage totaling up to 30% of maximum HP.ĭeals ice damage with a potency of 120 to target and all enemies nearby it.ĭeals lightning damage with a potency of 50.ĭeals fire damage to a target and all enemies nearby it with a potency of 220 for the first enemy, and 40% less for all remaining enemies.Ĭonnects naturally occurring ley lines to create a circle of power which, while standing within it, reduces spell cast time and recast time, and auto-attack delay by 15%.Įnsures the next Scathe, Fire, Paradox, or Thunder spell cast will, for the first hit, trigger Scathe's additional effect, Firestarter, or Thundercloud. 12/17/2023 0 Comments Exr headlight hd cleaner teview![]() ![]() Madeleine Burry has written for the Spruce since 2019, covering crafting, home, and pets. Using these can cause septic tank backups, contaminate your drinking water, and cause foul odors.” “Look for chlorine bleach or chemical sodium hypochlorite on product labels. If you use them too often, they can cause your septic tank to back up. If you have a septic tank, toilet bowl cleaners and bleach- or chlorine-based cleaners should be avoided or seldom used, says Griccino. If that’s the case, you may want a gentler, more natural product that requires a little more elbow grease. These chemicals can be dangerous if you have pets, kids, or a septic system. Just note: These types of toilet bowl cleaners tend to be stronger and have harsh ingredients like bleach that help remove the tough stains and kill bacteria. Look for a cleaner that’s marketed toward your particular need. The best toilet bowl cleaners are all effective for everyday cleaning, but if your toilet has hard water build-up or rust stains, you may need a specialty product that will target the root cause of the issue. Just remember: If you’re sensitive to synthetic fragrance, you may want to opt for an unscented cleaner. Toilet cleaners come in all types of fragrances, from more florals to citrus. Though scent doesn’t have any influence on efficacy, a pleasing aroma can make the dirty job a little more enjoyable. ![]() Finally, there are pods or discs that work in your toilet's tank every time you flush for hands-off cleaning that’s still effective enough for standard messes (i.e. There are also toilet bowl wands that come with disposable cleaning heads, eliminating the need for a brush-particularly nice if you’re skeeved out by storing a used wand. First, there are traditional cleaners-liquids or gels that you apply to the bowl then scrub with a toilet brush. There are several types of toilet bowl cleaners, each of which requires a varying level of effort on your part. What to Look for in a Toilet Cleaner Type But if you’re looking for a more versatile cleaning product that won’t break the bank, a single jug of Clorox Disinfecting Bleach ( view at Target) will do the job-and others, like laundry or cleaning your kitchen sink-just as well. Go with Clorox Toilet Bowl Cleaner With Bleach ( view at Amazon) for a highly-effective way to keep your toilet cleaned, disinfected, and deodorized. The Spruce Home Improvement Review Board. 12/17/2023 0 Comments Icare home tonometerTonometers that can accurately measure IOP at home without topical anesthetic are not common. Neither person would know anything had happened until the anesthetic wore off. Any physician will be reluctant to let a patient use an anesthetic at home, because if the eye is anesthetized for a home-based reading, there’s a risk that the person taking the pressure will injure the cornea. Most tonometers aren’t suited to home tonometry because they require anesthetizing the cornea. The first obstacle has only recently been overcome: Having available technology that can safely be used by patients at home. 20111)ĭespite the promise of home IOP monitoring, a number of obstacles have caused this idea to get off to a slow start. IOPs tended to be higher in the mornings and lower in the evenings for both normal and glaucoma patients. It’s helpful to measure a diurnal pressure curve over the course of a day in the clinic (if the patient can manage this), but some studies have shown that in adults the diurnal fluctuation may not be exactly the same from one day to the next. A single in-office diurnal curve measurement may not tell the whole story.For a patient measuring IOP at home, some office visits purely for IOP checks might actually be unnecessary. Patients who need to have their pressure checked sometimes can’t come to the office when, or as often, as we’d like. Fewer concerns about patients missing office visits.If IOP is being monitored at home during such high-risk times in vulnerable patients, we’ll know when there’s an abrupt pressure change that needs to be addressed. In the adult world, some MIGS procedures are also associated with pressure spikes. In the latter situation, the pressure may be very high until the stitch dissolves then it may drop very low. In the pediatric world, situations prone to such fluctuations might include doing angle surgery and having a little blood in the eye putting the child on steroids or putting in a Baerveldt drainage device where we purposely tie the tube off, knowing that it’s going to open when the stitch dissolves. Sometimes the treatments we pro-vide-including surgery-cause dramatic IOP fluctuations. Some fluctuations caused by surgery can be dangerous when they’re not carefully monitored. ![]() Measuring IOP over a larger range of time offers the possibility of catching those fluctuations. (This stands in contrast to patients whose IOPs are at target and stable.) We also know that pressure fluctuations can happen outside of office hours. It’s been shown that pressure fluctuations-even those measured during periodic office visits-are associated with progression in adult open-angle glaucoma. So it shouldn’t be a surprise-and it has been my experience-that multiple measurements taken outside of the office frequently reveal much higher pressures than we measured in the office. The variability of IOP over time sometimes surprises us occasionally, the pressure we measure in the office is very different from the previous visit.
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